Etoricoxib Dosage: What You Need to Know

Etoricoxib dosage determines how well this COX‑2 inhibitor controls pain while keeping side effects in check. When working with Etoricoxib dosage, the specific amount of etoricoxib prescribed for conditions like osteoarthritis, rheumatoid arthritis, or post‑surgical pain. Also called Arcoxia dosage, it helps doctors customize treatment based on age, weight, and organ function.

As a member of the COX‑2 inhibitors, drugs that selectively block the cyclooxygenase‑2 enzyme to reduce inflammation, etoricoxib shares a pharmacological family with celecoxib and parecoxib. These agents belong to the broader class of non‑steroidal anti‑inflammatory drugs, medications that lower pain and swelling by inhibiting prostaglandin synthesis. Knowing that COX‑2 inhibitors influence pain‑management outcomes helps clinicians weigh cardiovascular risk against analgesic benefit. The drug’s pharmacokinetic profile—rapid absorption within an hour, a half‑life of about 22 hours, and hepatic metabolism via CYP3A4—means once‑daily dosing is usually sufficient, but it also signals potential drug‑interaction alerts with certain antibiotics, antifungals, or statins. Adjustments become crucial when a patient has impaired kidney or liver function, because reduced clearance can raise plasma levels and increase the chance of gastrointestinal upset or edema.

Dosage Guides for Common Scenarios

Typical adult dosing for chronic joint pain starts at 60 mg once daily, covering the majority of osteoarthritis cases with good efficacy and tolerability. For rheumatoid arthritis, clinicians often increase to 90 mg daily, but they must monitor blood pressure and lipid profiles, as the relationship “Etoricoxib dosage – requires – cardiovascular monitoring” is well‑documented. After orthopedic surgery, a short‑term 120 mg dose can accelerate recovery, yet only under close supervision because high‑dose exposure requires renal function checks every 2–4 weeks. Patients with an estimated glomerular filtration rate (eGFR) below 30 mL/min usually need a 30 mg reduction, illustrating the triple “Etoricoxib dosage – requires – renal adjustment”. Elderly patients (>75 years) may start at 30 mg to reduce the risk of fluid retention and hypertension. If a patient is already taking another NSAID or an anticoagulant like warfarin, the dosage may be cut in half or the drug swapped altogether, reflecting the predicate “drug interaction – influences – dosage decision”. Side‑effects such as abdominal discomfort, mild liver enzyme elevation, or skin rash are generally dose‑dependent, so keeping the dose as low as effective is a practical rule.

The articles below dive deep into each of these dosing strategies, compare etoricoxib with other NSAIDs, and offer step‑by‑step tips for prescribers and patients. You’ll find tables that list starting doses, max doses, and specific adjustments for kidney disease, heart disease, and age. Whether you’re a clinician fine‑tuning a regimen or a patient looking for clear, actionable guidance, the collection ahead provides the answers you need to use etoricoxib safely and effectively.