Buy Zelboraf - Vemurafenib Related Medications

It has just been a year or so, since the drug Vemurafenib got approved by the major authorizing bodies of the first word countries. The medication got approved by the FDA in August, 2011 for the treatment of advanced stage melanoma. This was followed by the approvals from the ‘Health Canada’ and ‘European Commission’ in February 2012 for the same indication as mentioned. After the drug got approved by these major official bodies, a new path of hope opened for the melanoma patients, who found themselves uncomfortable with other prevailing treatmental courses. However, it is to be mentioned here that the drug is only effective in the treatment of patients who have BRAF V600 mutation positive unresectable or metastatic melanoma. The medication is not used in other types of melanoma; rather it is often contraindicated in such cases.

Nonetheless, like all drugs Vemurafenib also had to pass some Clinical Trials before being marketable. This included two trials for determining all the potential adverse effects of the drug. The first Clinical Trial included 675 subjects, who received 960mg of vemurafenib twice a day OR 1000mg/m2 of Dacarbazine intravenously every three weeks. The overall response rate was 48.4% in the Zelboraf Arm compared to 5.5% in the Dacarbazine arm. The median PFS of Vemurafenib arm was 5.3 months as compared to 1.6 months in the Dacarbazine arm. The Second Clinical Trial included 132 subjects, who previously had received any systematic treatment resulting in failure. The overall response rate was 52%. The median time to response was 1.4 months where as the median duration of response was 6.5 months.

So, once you are diagnosed with the BRAF V600 mutation positive unresectable or metastatic melanoma and are prescribed with vemurafenib, your very next step should be to find a legitimate pharmacy to buy Zelboraf from. While you have a number of options, where you could buy Zelboraf, Isrameds is one pharmacy that falls in the category of most acclaimed, well known and trustworthy pharmacies of the world. When you decide on Isrameds to buy Zelboraf supply from, you are assured of a superior quality of service and an unparalleled experience of dealing with an online pharmacy. Since, online pharmacies themselves are given an upper hand over the real (brick and mortar) pharmacy – on grounds that an online pharmacy wouldn’t charge you a dime in the name of continuance taxes and other random charges – getting your drug from a pharmacy of Isrameds’ caliber would be more like icing on the cake.

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